Systems Biology Collaboration Center (SBCC)
Acting Director: Dr. Frank J. Lebeda, Ph.D.
The SBCC is a distinct office hosted at the US Army Center for Environmental Health Research (USACEHR) that facilitates
systems biology collaborations and supports a centralized data sharing and integration infrastructure for USAMRMC
investigators and partnering investigators at other Army, DoD, and extramural organizations.
The SBCC conducts these activities in accordance with the vision, mission, objectives, and milestones of the Systems
Biology Enterprise (SBE). The SBE established within the U.S. Army Medical Research and Materiel Command (USAMRMC) is
the Army's activity designed to build and maintain a competency in medical systems biology science and technology (S&T)
and apply these capabilities to all applicable areas of MRMC research and development responsibility, as appropriate.
Systems biology (SB) is an approach that integrates experimental and clinical Big Data (multi-omics) with computational
models that has become the foundation of predictive and personalized medicine.
The SBCC provides guidance and oversight of the SysBioCube,
the USAMRMC's big data/omics information management suite, hosted by the National Cancer Institute (NCI)/National Institutes
of Health (NIH) via the Frederick National Laboratory for Cancer Research (FNLCR). It includes a biomedical research data
repository, data integration and analysis tools, and networked portal to link databases to computational biology analysis tools.
- Foster and integrate USAMRMC-initiated systems biology collaborative science teams
- Facilitate, plan, coordinate, assess, and oversee USAMRMC-wide data and database quality, security, sharing, networking,
and analytical resources
- Plan, coordinate, and manage the potential expansion to integrate collaborative science and/or data and database utilization
with other DoD RDT&E performers
Integration of personalized, predictive, preventive and participatory medicine (including performance optimization) into
standard Army personal health and medical practices.
Facilitate development of computational tools and the accumulation of integrative systems biology and network science
medical research outcomes, data, and models that complement the Army's medical research programs.
Federal and DoD Data Sharing Policies:
- Holdren, J.P. White House Office of Science and Technology Policy memorandum,
Access to the Results of Federally Funded Scientific Research" (February 22, 2013)
- Executive Order 13642 "Making
open and machine readable the new default for Government information" (May 2013)
- OMB "M-13-13
Open Data Policy- Managing Information as an Asset" (May 2013)
- Kendall, F. Under Secretary of Defense for Acquisition, Technology and Logistics memo
"Public Access to the Results of Department of
Defense-Funded Research" (July 09, 2014)
- DoD, "Plan to Establish Public Access
to the Results of Federally Funded Research" (February, 2015)
- Interagency Working Group on Open Data Sharing Policy of the Subcommittee on International Issues of the Committee on Science
of the National Science and Technology Council,
for Promoting Access to Federal Government-Supported Scientific Data and Research Findings Through International Scientific
Cooperation" (December 2016)
- Kendall, F. Directive-type Memorandum (DTM) 17-002 – Public
Access to the Results of DoD Intramural Basic Research Published in Peer Reviewed Scholarly Publications (January 10, 2017)
Army research centers:
- USAMRMC Program Area Directorates and Research Coordinating Offices:
- USAMRMC Laboratories:
- Other USAMRMC Organizations:
Army-sponsored University Affiliated Research Centers (UARC):